The show revolves around the adventures of the family of Peter Griffin, a bumbling, but well-intentioned, blue-collar worker. Peter is an Irish American Catholic with a prominent Rhode Island and Eastern Massachusetts accent.He is married to Lois, a stay-at-home mother and piano teacher, who has a distinct New England accent from being a member of the Pewterschmidt family of wealthy socialites. Peter and Lois have three children: Meg, their teenage daughter, who is awkward and does not fit in at school; Chris, their teenage son, who is overweight, unintelligent and, in many respects, a younger version of his father; and Stewie, their diabolical infant son of ambiguous sexual orientation who has adult mannerisms, and speaks fluently with stereotypical archvillain phrases. Living with the family is Brian, the family dog, who is highly anthropomorphized, drinks martinis and engages in human conversation, though he is still considered a pet in many respects.Many recurring characters appear alongside the Griffin family. These include the family's neighbors: sex-crazed airline-pilot bachelor Glenn Quagmire, Cleveland Brown and his wife Loretta Brown, paraplegic police officer Joe Swanson, his wife Bonnie and their baby daughter Susie (it should be noted that Bonnie is pregnant with Susie from the show's beginning until the 7th episode of the 7th season); paranoid Jewish pharmacist Mort Goldman, his wife Muriel and their geeky and annoying son Neil; and elderly ephebophile Herbert. TV news anchors Tom Tucker and Diane Simmons, Asian reporter Tricia Takanawa, and Blaccu-Weather meteorologist Ollie Williams also make frequent appearances. Quahog mayor, Mayor Adam West, is in various episodes.

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